LONDON, 21st September, 2020 – A new academic study has revealed that a patented formulation of fibres and a mineral may help consumers manage their weight by reducing cravings for sweet and savoury foods. The study shows the formulation, developed with leading UK universities, helps consumers modify the amount and type of food they eat so they can effectively manage their weight as part of a healthy lifestyle.
The study, conducted by the University of Roehampton, was a 4-week pilot human intervention aimed to observe the effect of SlimBiome®, a patented formulation of glucomannan, oligofructose and chromium, on weight loss, satiety, mood and gut microbiota in 12 obese and overweight women aged between 18-65 years.
Each of the 12 volunteers were asked to follow a 1,500-calorie restricted diet plan using a range of nutritionally diverse foods, incorporating meal replacement shakes and snack bars containing the patented formulation throughout the day, alongside a healthy dinner of their choice.
The results showed that SlimBiome significantly reduced body weight, BMI, fat mass, waist and hip circumference, and systolic blood pressure. The improvements in body composition appear to result from the significant reduction in percentage body fat as there was no change in total body water in study participants. Study participants showed a reduction in sweet cravings and a statistically significant reduction in savoury cravings. This was accompanied by a statistically significant improvement in mood, possibly due to the fact participants were losing weight without food cravings, and a positive impact on gut microbiome composition.
Adele Costabile, Associate Professor (Reader) in Nutrition and Life Sciences at the University of Roehampton, commented: “Overweight and obesity is a global pandemic with a high prevalence that affects both developed and developing countries. In 2020, the Statistics on Obesity, Physical Activity and Diet, England report by the NHS found the majority of adults were overweight or obese. Furthermore, the report stated that 26% of men and 29% of women were classed as obese. While the causes of obesity are multifactorial, the imbalance between energy intake and expenditure remains the main driver of the obesity epidemic.
“Traditionally speaking, consumers are less likely to maintain their weight goals when they rely on willpower alone. The very nature of yo-yo dieting is down to a lack of support for consumers, since their eating habits are influenced by emotional and psychological stress, further encouraging the intake of calorie-dense comfort foods. This means the more we can develop functional ingredients which helps consumer to control their mood, hunger and cravings, the more likely they are to achieve successful and sustainable weight loss.
“Our study demonstrates that this ingredient combination is an effective means of supporting consumer weight loss goals, as it helps them to help themselves. The study showed taking SlimBiome® for 4 weeks led to significantly reduced body weight (average 1.9kg), fat mass, body fat percentage, waist and hip circumference, systolic blood pressure, cravings for savoury and sweet foods and was accompanied by improvements in mood and gut microbiome diversity.”
SlimBiome, the main ingredient used in the study, is available from OptiBiotix Health Plc. Supplied as an ingredient for food manufacturers, as well as in supplement form. The company also uses it as an ingredient in its finished consumer products range, GoFigure®, that includes meal-replacement shakes, flapjacks and muesli. Consumers are able to take this nutritional blend to control hunger cravings with any calorie-controlled diet plan, such as intermittent fasting, low-carbohydrate or plant-based diets.
“The results of this independent pilot study are promising,” added Stephen O’Hara, CEO at OptiBiotix, “and may help provide additional support to individuals looking to reduce weight and risk amidst the COVID-19 pandemic. The findings of this study suggest consumers can control their weight through any calorie restricted diet plan, without having to rely on willpower alone. We hope this will help reduce the burden of dieting and increase the likelihood of success.”
OptiBiotix was formed in March 2012 to develop microbial strains and formulations, which modulate the human microbiome and can be used as food ingredients and supplements for the prevention and management of human metabolic diseases, including obesity, cholesterol and diabetes.
To view the study in full, please visit: https://www.sciencedirect.com/science/article/pii/S1756464620303819.
For more information on OptiBiotix, visit: https://optibiotix.com/.